Research Technician - Bourret Lab

Monday - Friday, 8am-5pm

To learn more about the pay band for this branch and role, please see the Career Banding rates spreadsheet.

A global higher education leader in innovative teaching, research and public service, the University of North Carolina at Chapel Hill consistently ranks as one of the nation's top public universities. Known for its beautiful campus, world-class medical care, commitment to the arts and top athletic programs, Carolina is an ideal place to teach, work and learn.

One of the best college towns and best places to live in the United States, Chapel Hill has diverse social, cultural, recreation and professional opportunities that span the campus and community.

University employees can choose from a wide range of professional training opportunities for career growth, skill development and lifelong learning and enjoy exclusive perks for numerous retail, restaurant and performing arts discounts, savings on local child care centers and special rates on select campus events. UNC-Chapel Hill offers full-time employees a comprehensive benefits package, paid leave, and a variety of health, life and retirement plans and additional programs that support a healthy work/life balance.

Our mission is to improve the health and well-being of North Carolinians and others whom we serve. We accomplish this by providing leadership and excellence in the interrelated areas of patient care, education and research.

Patient care: We promote health and provide superb clinical care while maintaining our strong tradition of reaching underserved populations and reducing health disparities across North Carolina and beyond.

Education: We prepare tomorrow's healthcare professionals and biomedical researchers from all backgrounds by facilitating learning within innovative and integrated curricula and team-oriented interprofessional education to ensure a highly skilled workforce.

Research: We develop and support a rich array of outstanding health sciences research programs, centers and resources. We provide infrastructure and opportunities for collaboration among disciplines throughout and beyond our university to support outstanding research. We foster programs in the areas of basic, translational, mechanistic and population research.

THIS IS A TIME-LIMITED POSITION WITH AN ESTIMATED DURATION OF 1 YEAR.

Research in the Bourret laboratory primarily investigates the molecular mechanisms of signal transduction by two-component regulatory systems in bacteria. The employee will conduct a research project under the supervision of Dr. Bourret. The employee will also help develop assays for the ADP-ribose hydrolase activity of alphavirus nsP3 macrodomains. Methods for both topics will mostly involve protein purification and measurement of enzyme kinetics. With suitable training and close supervision, the employee might perform experiments using 32P radioisotope. Participation in weekly group meetings to describe results, as well as discuss results of other lab members, is expected.

Demonstrated possession of the competencies necessary to perform the work.

Must be able to work and communicate well with other lab members. Must be able to keep accurate notes of experiments performed. Must have good time management skills. Must be able to work with minimal supervision following appropriate training. Must have the flexibility to occasionally work briefly on nights or weekends to keep experiments progressing in a timely manner.

Laboratory research experience outside of coursework. Laboratory research experience in biochemistry, microbiology, and/or molecular biology is strongly preferred. Experience with protein purification using nickel affinity chromatography. Experience with protein purification using an AKTA protein purification system. Experience with mass photometry would be an asset. Preferred candidate with have knowledge of the biological sciences. Coursework in microbiology, genetics, and molecular biology is strongly preferred. Chemistry coursework through organic chemistry and biochemistry is strongly preferred. Mathematics coursework through calculus is strongly preferred. Coursework in statistics would be an asset. Familiarity with bioinformatics methods and software for analysis of protein sequences and structures would be an asset. Familiarity with PyMol protein structure visualization software would be an asset. Familiarity with GraphPad Prism statistical analysis software would be an asset. Preferred can use Microsoft Office (Word, Excel, PowerPoint).

Not Applicable.

If you experience any problems accessing the system or have questions about the application process, please contact the Office of Human Resources at (919) 843-2300 or send an email to employment@unc.edu

Please note: The Office of Human Resources will not be able to provide specific updates regarding position or application status.

The University is an equal opportunity employer and welcomes all to apply without regard to age, color, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, or sexual orientation. We encourage all qualified applicants to apply, including protected veterans and individuals with disabilities.